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- Post-Doctoral Research Fellow - Immunology
Description
Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.
With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.
At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.
We are looking to hire a PhD or MD/PhD scientist with strong training in immunology and/or hematopoietic stem cell biology, who is motivated to develop a research trajectory in cord blood transplantation and immune reconstitution. The successful candidate will receive close scientific mentorship while being encouraged to progressively develop independence in experimental design, data analysis, and project leadership. This individual should be able to work productively within a mentored framework while demonstrating the initiative and critical thinking skills needed to drive projects forward. They will contribute meaningfully to team-based science, including collaborations with clinicians, bioinformaticians, and shared resource cores, with the long-term goal of developing an independent scientific profile.
Responsibilities
- Study the function and persistence of T cells in clinical trial patients
- Organize and track patient samples, assays, and data
- Cell Culture, cell sorting, flow cytometry, intracellular staining, and transfections
- Molecular bench work with PCR, cloning, and vector design
- NGS including, Single cell RNA sequencing, WEX, WGS
- Biostatistics and some basic programming
- Validation through functional and killing assays
- Write and submit grants and first author papers to peer reviewed journals
- Stay current with relevant publications and apply knowledge to research
- Compile data and synthesize innovative problem-solving methods
- Collaborate and present data with a wide range of stakeholders and partners
- Train others on protocols
- Mentor and lead undergraduate and graduate students
- Assist with lab maintenance and function
Requirements
MINIMUM QUALIFICATIONS:
- MD and/or a PhD in a biological science with a diverse knowledge of immunology
- Proficient in immunology technique and knowhow
- Strong scientific writing skills, ability to write and apply for funding opportunities and abstracts
- Able to digest complex material and synthesize innovative ideas
- Compile and clearly present data to an eclectic audience, both orally and written
- Well versed in flow cytometry
PREFERRED QUALIFICATIONS:
- Strong training in immunology and/or hematopoietic stem cell biology
- Experience with molecular techniques lentiviral modification of T cells
- Experience in analysis of TCR signaling pathways and T cell function
- Familiarity with biostatistics, R and Python languages
- Ability to derive and maintain T cell tissue cultures
- Have a good understanding of SRAs and/or phase I/II clinical trials
- Comfortable with vivo models and working at the interface of wet-lab experimentation and quantitative data analysis
The annual base salary range for this position is from $80,172 to $95,014, and pay offered will be based on experience and qualifications.
This position is not eligible for H-1B sponsorship at this time.
